Clinical Studies
Introduction
Origin Sciences regularly sponsors a variety of clinical studies
We sponsor studies across a number of UK Primary and Secondary Care NHS sites in the UK (and occasionally in other territories).
To date, over 3,000 patients have taken part in studies that we have sponsored
We are grateful for the continuing participation of so many study patients, who are helping us to investigate gastrointestinal diseases for the benefit of future patients. In addition our medical devices are used in research sponsored by third parties conducting their own research.
Participants
Taking part in a study
If you have been asked to take part in one of these studies, any queries or concerns that you may have must be directed to either the study lead investigator or any other clinical professional involved in the specific study. Unfortunately the staff at Origin Sciences are unable to communicate directly with any study participants or potential participants, and are unable to provide any advice regarding the study.
All active studies have full and relevant ethical approval, and have been carefully designed to ensure safe delivery. Participating in our studies is always optional, and participation can be withdrawn at any time.
Participants are not usually paid for their participation in our studies (occasionally and under certain circumstances we may pay expenses). Your participation is however extremely valuable in helping us to understand various ailments of the gastrointestinal tract and deliver new diagnostic solutions with the ultimate aim of saving lives through earlier detection and distinction of disease.
Current Studies
Feasibility Study to Investigate Rectal Mucus in Aero-Digestive Tract Cancer
The primary objective of the study is to assess whether significant changes in DNA mutation and methylation associated with Non-colorectal cancers of the Aero- digestive Tract (NCRCADT) can be detected in rectal mucus as shed cells and cell-free DNA (cfDNA) pass through the gut and theoretically can be collected from rectal mucus.
An Exploratory Study Investigating the Potential of a Rectal Mucus Sample for Development of Biomarker Assays in Subjects With Gastrointestinal Diseases
It is our aim to develop a novel diagnostic device based upon the identification of genetic mutations and genomic alterations from material trapped in the rectal mucous layer allowing focused endoscopic assessment, confirmation/exclusion of cancer diagnosis from cross-sectional imaging in those unfit for endoscopic examination and identification of high-risk lesions (dysplasia).